
70x – 170x stronger local exposure of the tumor

Reducing chemo levels up to 1000 times to the rest of the body

Can deliver almost anywhere in the body

Wide range of drugs suitable for this local delivery platform

Affordable treatment
The most direct way of targeting tumors, and still minimally invasive
Dealing with primary tumors or metastasized tumors posing an immediate threat to vital functions can be a major challenge in managing tumor disease and the well-being of your patients. Our injectable drug depots target the tumor in the most direct manner possible: injecting a drug depot inside the tumor mass.
This is a magnificent opportunity for reward and for impact in oncology. You have heard it all before, we are sure of that. So, we derisked the ChemoGell™ proposition to a considerable length and kept it attractive to step in early and make your ROI count. Even better, we are goint to prove this to you with our led product ChemGem to deal with one of the most notorious cancers ut there: Pancreatic cancer, more specifically PDAC.
Direct delivery, as targeted as your drug discovery will ever be…
(After having identified and developed a new oncology drug), With your new oncology drug candidate you need to deliver your asset where it makes most sense, and at the most optimal price point… In many cases we see major opportunities for advanced delivery in, or near, the tumor mass that you target.
Turning drug delivery in oncology upside down, treating Tumors from the Inside
What if we can turn oncology drug delivery upside down? To deliver oncology drugs locally, inside the targeted tumors, where they should be. And then keep them there, increase efficacy in eradication of tumors, reduce the serious side effects and the total cost of care?
OncoLize develops injectable drug depots to deliver oncology drugs where they matter most: inside tumors.
We have shown the concept to work in relevant animal models, we have first patents granted and in advanced national stages and we can scale-up these products at minimal costs. With our extensive experience in setting-up controlled delivery start-up’s we aim to exit at year 6.
That being said, we at OncoLize believe and practice that our products should have impact for global issues. We will make these products available for campaigns in Low- and Middle Income Countries through focused NGO-collaborations.
Our Team

CEO
The company was founded by Mike de Leeuw (CEO), who previously founded InGell Labs (2010), Branching Tree (2008) and DSM BioMedical (2005) and has a track record in re-structuring and re-financing other start-up’s within the controlled release/ biomedical materials space for drug delivery and cell therapy.

CTO
Mike is joined by dr. Leo de Leede (CTO), a long-time biopharmaceutical expert using polymer-enabled drug delivery in a.o. Organon/MSD – Yamanuchi/Astellas – OctoPlus/Dr.Reddy – Branching Tree/ InGell Labs.

CSO
As of April 2023 they are joined by Helena Kelly (CSO), full time professor at RCSI and the inventor of the licensed OncoLize Technology platform.
NEWS
Our developments reported by the press
5th September 2024
Drug delivery start-up OncoLize (NL) achieved a remarkable 100% survival rate and growth arrest in a PDX-mouse model using its ChemGemTM on rapidly growing human pancreatic tumors in collaboration with Leiden University Medical Center.
12th September 2024
Pharma-tech OncoLize is pitching its recent successes in pre-clinical pancreatic cancer treatment at RESI , PODD and Bio-Europe to complete its seed round with €1.5 million in order to finalize its safety and tox studies, scale-up to cGMP grade and preprare for Clinical Trial Application.
15th August 2024
The base patents covering the ChemoGellTM platform has been granted by USPTO, China PTO and JPTO. These broad base patents describe the composition-of-matter and various formulations and applications essential to the oncology business.

